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1

High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner

Polansky, Julia K., Bahri, Rajia, Divivier, Mylene, Duitman, Erwin H., Vock, Christina, Goyeneche-Patino, Diego A., Orinska, Zane, Bulfone-Paus, Silvia

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

2

Novel B cell population producing functional IgG in the absence of membrane IgM expression

Zane Orinska, Anna Osiak, Jürgen Löhler, Elena Bulanova, Vadim Budagian, Ivan Horak, Silvia Bulfone-Paus

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 523 KB

english, 2002

3

IL-2 induces in vivo suppression by CD4+CD25+Foxp3+ regulatory T cells

Susan Brandenburg, Takeshi Takahashi, Maurus de la Rosa, Marko Janke, Gabriele Karsten, Till Muzzulini, Zane Orinska, Silvia Bulfone-Paus, Alexander Scheffold

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 403 KB

english, 2008

4

Mast cells secrete IL-15 by microvesicles shedding upon P2X7 receptor stimulation

E Bulanova, V Budagyan, Z Orinska, M Klinger, S Bulfone-Paus

Journal:

Cell Communication and Signaling

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

5

Mast Cell-Mediated Antigen Presentation Regulates CD8+ T Cell Effector Functions

Erietta Stelekati, Rajia Bahri, Orietta D'Orlando, Zane Orinska, Hans-Willi Mittrücker, Rabea Langenhaun, Markus Glatzel, Annalena Bollinger, Ralf Paus, Silvia Bulfone-Paus

Journal:

Year:

2009

Language:

english

File:

PDF, 969 KB

english, 2009

6

A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control

Budagian, Vadim, Bulanova, Elena, Orinska, Zane, Thon, Lutz, Mamat, Uwe, Bellosta, Paola, Basilico, Claudio, Adam, Dieter, Paus, Ralf, Bulfone-Paus, Silvia

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

7

IL-15 constrains mast cell–dependent antibacterial defenses by suppressing chymase activities

Orinska, Zane, Maurer, Marcus, Mirghomizadeh, Farhad, Bulanova, Elena, Metz, Martin, Nashkevich, Natalia, Schiemann, Florian, Schulmistrat, Jan, Budagian, Vadim, Giron-Michel, Julien

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 417 KB

english, 2007

8

A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control

Budagian, Vadim, Bulanova, Elena, Orinska, Zane, Thon, Lutz, Mamat, Uwe, Bellosta, Paola, Basilico, Claudio, Adam, Dieter, Paus, Ralf, Bulfone-Paus, Silvia

Journal:

The EMBO Journal

Year:

2005

Language:

english

File:

PDF, 347 KB

english, 2005

9

Mechanisms of cytokine secretion: A portfolio of distinct pathways allows flexibility in cytokine activity

Erwin Hans Duitman, Zane Orinska, Silvia Bulfone-Paus

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 490 KB

english, 2011

10

Intracellular IL-15 controls mast cell survival

Farhad Mirghomizadeh, Supandi Winoto-Morbach, Zane Orinska, Kyeong-Hee Lee, Stefan Schütze, Silvia Bulfone-Paus

Journal:

Experimental Cell Research

Year:

2009

Language:

english

File:

PDF, 830 KB

english, 2009

11

114 IL-15 Constrains Mast Cell-dependent Anti-bacterial Defenses by Suppressing Chymase Activities

Zane Orinska, Marcus Maurer, Farhad Mirghomizadeh, Elena Bulanova, Martin Metz, Florian Schiemann, Jan Schulmistrat, Julien Giron-Michel, Ernst Brandt, Silvia Bulfone-Paus

Journal:

Year:

2007

Language:

english

File:

PDF, 52 KB

english, 2007

12

Mast cells in allergy: Innate instructors of adaptive responses

Erietta Stelekati, Zane Orinska, Silvia Bulfone-Paus

Journal:

Year:

2007

Language:

english

File:

PDF, 518 KB

english, 2007

13

Syntaxin 11 is required for NK and CD8 + T-cell cytotoxicity and neutrophil degranulation

D'Orlando, Orietta, Zhao, Fang, Kasper, Brigitte, Orinska, Zane, Müller, Jürgen, Hermans-Borgmeyer, Irm, Griffiths, Gillian M., Zur Stadt, Udo, Bulfone-Paus, Silvia

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

14

Binding of Nerve Growth Factor to Different Forms of α2-Macroglobulin

KLAUS KECK, ZANE ORINSKA, MICHAELA WALDSCHÜTZ

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 183 KB

english, 1994

15

Long-Term Bortezomib Treatment Reduces Allergen-Specific IgE but Fails to Ameliorate Chronic Asthma in Mice

Wegmann, Michael, Lunding, Lars, Orinska, Zane, Wong, David M., Manz, Rudolf A., Fehrenbach, Heinz

Journal:

International Archives of Allergy and Immunology

Year:

2012

Language:

english

File:

PDF, 849 KB

english, 2012

16

TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment

Journal:

Year:

2005

Language:

english

File:

PDF, 487 KB

english, 2005

17

IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation

Sandig, Hilary, Jobbings, Catherine E., Roldan, Nestor Gonzalez, Whittingham-Dowd, Jayde K., Orinska, Zane, Takeuchi, Osamu, Akira, Shizuo, Bulfone-Paus, Silvia

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 991 KB

english, 2013

18

miRNA-155 controls mast cell activation by regulating the PI3Kγ pathway and anaphylaxis in a mouse model

Biethahn, K., Orinska, Z., Vigorito, E., Goyeneche-Patino, D. A., Mirghomizadeh, F., Föger, N., Bulfone-Paus, S.

Journal:

Year:

2014

Language:

english

File:

PDF, 607 KB

english, 2014

19

Retraction: Mast Cells Express Novel Functional IL-15 Receptor Isoforms

Krause, H., Paus, R., Orinska, Z., Bulfone-Paus, S.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 538 KB

english, 2011

20

Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF- B.

Budagian, V., Bulanova, E., Brovko, L., Orinska, Z., Fayad, R., Paus, R., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 609 KB

english, 2011

21

Soluble interleukin (IL)-15Rα is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.

Bulanova, Elena, Budagian, Vadim, Duitman, Erwin, Orinska, Zane, Krause, Hans, Rückert, Rene, Reiling, Norbert, Bulfone-Paus, Silvia

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 513 KB

english, 2011

22

A Regulatory Role for CD37 in T Cell Proliferation

van Spriel, A. B., Puls, K. L., Sofi, M., Pouniotis, D., Hochrein, H., Orinska, Z., Knobeloch, K.-P., Plebanski, M., Wright, M. D.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 778 KB

english, 2004

23

Natural soluble interleukin-15R is generated by cleavage that involves the tumor necrosis factor- -converting enzyme (TACE/ADAM17).

Budagian, V., Bulanova, E., Orinska, Z., Ludwig, A., Rose-John, S., Saftig, P., Borden, E. C., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 148 KB

english, 2011

24

Survival and Migration of Human Dendritic Cells Are Regulated by an IFN- -Inducible Axl/Gas6 Pathway

Scutera, S., Fraone, T., Musso, T., Cappello, P., Rossi, S., Pierobon, D., Orinska, Z., Paus, R., Bulfone-Paus, S., Giovarelli, M.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

25

Reverse Signaling through Membrane-bound Interleukin-15

Budagian, V., Bulanova, E., Orinska, Z., Pohl, T., Borden, E. C., Silverman, R., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.17 MB

english, 2004

26

Retraction: Extracellular ATP Induces Cytokine Expression and Apoptosis through P2X7 Receptor in Murine Mast Cells

Orinska, Z., Hein, M., Petersen, F., Bulfone-Paus, S., Thon, L., Adam, D.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 20 KB

english, 2011

27

Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b

Foger, N., Jenckel, A., Orinska, Z., Lee, K.-H., Chan, A. C., Bulfone-Paus, S.

Journal:

Journal of Experimental Medicine

Year:

2011

Language:

english

File:

PDF, 2.94 MB

english, 2011

28

Transcriptional Regulation of Mouse Mast Cell Protease-2 by Interleukin-15

Mirghomizadeh, F., Bullwinkel, J., Orinska, Z., Janssen, O., Petersen, A., Singh, P. B., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 4.49 MB

english, 2009

29

Soluble Axl Is Generated by ADAM10-Dependent Cleavage and Associates with Gas6 in Mouse Serum

Budagian, V., Bulanova, E., Orinska, Z., Duitman, E., Brandt, K., Ludwig, A., Hartmann, D., Lemke, G., Saftig, P., Bulfone-Paus, S.

Journal:

Molecular and Cellular Biology

Year:

2011

Language:

english

File:

PDF, 19 KB

english, 2011

30

Soluble Interleukin (IL)-15R Is Generated by Alternative Splicing or Proteolytic Cleavage and Forms Functional Complexes with IL-15

Bulanova, E., Budagian, V., Duitman, E., Orinska, Z., Krause, H., Ruckert, R., Reiling, N., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.30 MB

english, 2007

31

How a Cytokine Is Chaperoned through the Secretory Pathway by Complexing with Its Own Receptor: Lessons from Interleukin-15 (IL-15)/IL-15 Receptor

Duitman, E. H., Orinska, Z., Bulanova, E., Paus, R., Bulfone-Paus, S.

Journal:

Molecular and Cellular Biology

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

32

How a Cytokine Is Chaperoned through the Secretory Pathway by Complexing with Its Own Receptor: Lessons from Interleukin-15 (IL-15)/IL-15 Receptor

Duitman, E. H., Orinska, Z., Bulanova, E., Paus, R., Bulfone-Paus, S.

Journal:

Molecular and Cellular Biology

Year:

2010

Language:

english

File:

PDF, 19 KB

english, 2010

33

Natural Soluble Interleukin-15Rα Is Generated by Cleavage That Involves the Tumor Necrosis Factor-α-converting Enzyme (TACE/ADAM17)

Budagian, Vadim, Bulanova, Elena, Orinska, Zane, Ludwig, Andreas, Rose-John, Stefan, Saftig, Paul, Borden, Ernest C., Bulfone-Paus, Silvia

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1021 KB

english, 2004

34

Deficiency of the Tetraspanin CD63 Associated with Kidney Pathology but Normal Lysosomal Function

Schroder, J., Lullmann-Rauch, R., Himmerkus, N., Pleines, I., Nieswandt, B., Orinska, Z., Koch-Nolte, F., Schroder, B., Bleich, M., Saftig, P.

Journal:

Molecular and Cellular Biology

Year:

2009

Language:

english

File:

PDF, 2.97 MB

english, 2009

35

Mast Cells Express Novel Functional IL-15 Receptor Isoforms

Bulanova, E., Budagian, V., Orinska, Z., Krause, H., Paus, R., Bulfone-Paus, S.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 1.08 MB

english, 2003

36

Extracellular ATP Induces Cytokine Expression and Apoptosis through P2X7 Receptor in Murine Mast Cells

Bulanova, E., Budagian, V., Orinska, Z., Hein, M., Petersen, F., Thon, L., Adam, D., Bulfone-Paus, S.

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 586 KB

english, 2005

37

Signaling through P2X7 Receptor in Human T Cells Involves p56lck, MAP Kinases, and Transcription Factors AP-1 and NF- B

Budagian, V., Bulanova, E., Brovko, L., Orinska, Z., Fayad, R., Paus, R., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 668 KB

english, 2003

38

Targeted Inactivation of the Tetraspanin CD37 Impairs T-Cell-Dependent B-Cell Response under Suboptimal Costimulatory Conditions

Knobeloch, K.-P., Wright, M. D., Ochsenbein, A. F., Liesenfeld, O., Lohler, J., Zinkernagel, R. M., Horak, I., Orinska, Z.

Journal:

Molecular and Cellular Biology

Year:

2000

Language:

english

File:

PDF, 221 KB

english, 2000

39

Reverse signaling through membrane-bound interleukin-15.

Budagian, V., Bulanova, E., Orinska, Z., Pohl, T., Borden, E. C., Silverman, R., Bulfone-Paus, S.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 518 KB

english, 2011

40

Soluble Axl Is Generated by ADAM10-Dependent Cleavage and Associates with Gas6 in Mouse Serum

Budagian, V., Bulanova, E., Orinska, Z., Duitman, E., Brandt, K., Ludwig, A., Hartmann, D., Lemke, G., Saftig, P., Bulfone-Paus, S.

Journal:

Molecular and Cellular Biology

Year:

2005

Language:

english

File:

PDF, 867 KB

english, 2005

41

CD81 IS PART OF THE LPS RECEPTOR COMPLEX

Heine, Holger, Malzan, Artur, Nötzel, Corinna, Orinska, Zane, Reiling, Norbert, Brade, Lore, Schmitz, Gerd, Bulfone-Paus, Silvia, Ulmer, Artur J

Journal:

Year:

2004

File:

PDF, 102 KB

2004

42

CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice

Gonzalez Roldan, Nestor, Orinska, Zane, Ewers, Hanno, Bulfone-Paus, Silvia

Journal:

European Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

43

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development

Orinska, Z., Foger, N., Huber, M., Marschall, J., Mirghomizadeh, F., Du, X., Scheller, M., Rosenstiel, P., Goldmann, T., Bollinger, A., Beutler, B. A., Bulfone-Paus, S.

Journal:

Year:

2010

Language:

english

File:

PDF, 754 KB

english, 2010

44

Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory

Reitz, Martina, Hartmann, Wiebke, Rüdiger, Nikolas, Orinska, Zane, Brunn, Marie-Luise, Breloer, Minka

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.44 MB

english, 2018

45

Ectonucleotidase CD38 Demarcates Regulatory, Memory-Like CD8+ T Cells with IFN-γ-Mediated Suppressor Activities

Bahri, Rajia, Bollinger, Annalena, Bollinger, Thomas, Orinska, Zane, Bulfone-Paus, Silvia, Hasenkrug, Kim J.

Journal:

Year:

2012

Language:

english

File:

PDF, 730 KB

english, 2012

46

Nuclear Localization of Suppressor of Cytokine Signaling-1 Regulates Local Immunity in the Lung

Zimmer, Jana, Weitnauer, Michael, Boutin, Sébastien, Küblbeck, Günter, Thiele, Sabrina, Walker, Patrick, Lasitschka, Felix, Lunding, Lars, Orinska, Zane, Vock, Christina, Arnold, Bernd, Wegmann, Micha

Journal:

Frontiers in Immunology

Year:

2016

Language:

english

File:

PDF, 4.50 MB

english, 2016

47

C5a receptor 1 -/- mice are protected from the development of IgE-mediated experimental food allergy

Kordowski, Anna, Reinicke, Anna T., Wu, David, Orinska, Zane, Hagemann, Philipp, Huber-Lang, Markus, Lee, Jee-Boong, Wang, Yui-Hsi, Hogan, Simon P., Köhl, Jörg

Journal:

Year:

2018

Language:

english

File:

PDF, 869 KB

english, 2018

48

Lipid Mediators From Timothy Grass Pollen Contribute to the Effector Phase of Allergy and Prime Dendritic Cells for Glycolipid Presentation

González Roldán, Nestor, Engel, Regina, Düpow, Sylvia, Jakob, Katharina, Koops, Frauke, Orinska, Zane, Vigor, Claire, Oger, Camille, Galano, Jean-Marie, Durand, Thierry, Jappe, Uta, Duda, Katarzyna A.

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 1.24 MB

english, 2019

49

Tetraspanins in the regulation of mast cell function

Orinska, Zane, Hagemann, Philipp M., Halova, Ivana, Draber, Petr

Journal:

Medical Microbiology and Immunology

Year:

2020

File:

PDF, 1.05 MB

2020